Objective To observe and evaluate the clinic efficacy and safety of Ceftazidime for injection in treament of 80 patients with bacterial diseases. Methods The clinical effect of Ceftazidime and ADR on 80 bacterial patients was observed. Results The clinic investigation indicated that Ceftazidime gained satisfied clinic overall cure rate of Ceftazidime was 86.2%,and the overall effications rate was 96.1%.Besides,the rate of adverse reaction of Ceftazidime is only 3.7%,which is very low. Conclusion Ceftazidime is an effective and safe antibiotic for clinical use.