OBJECTIVE: To investigate the related factors that may influence the effect hearing aid for sensorineural hearing loss patients. METHOD: Sixty cases with moderate to severe sensorineural hearing loss were selected. Audiological measurements were performed before and after hearing aiding. Factor analysis was carried out. RESULT: The unaided hearing level (UHL), Speech perception thresher (SPT), speech recognition thresher (SRT), speech recognition score (SRS) and aided hearing level (AHL) have notable influence on the effect of hearing aid fitting. The most comfortable level (MCL), age, education period, hearing loss duration and aided duration also have some influence on the results. CONCLUSION: Hearing aid is not only a hearing compensating tool, it also has some therapeutic effect as well.