Fast and Selective Oxidation of Sulfides to Sulfoxides Catalyzed by Cerium (IV) Ammonium Nitrate

ABSTRACT The fast and selective oxidation protocol using cerium ammonium nitrate (CAN) in acetonitrile (MeCN) under ambient temperature and pressure was established. The primary features of this protocol include excellent substrate adaptability, gram‐scale preparation with high productivity, and fast and selective oxidation of sulfides to sulfoxides. The mechanism of this reaction was demonstrated to involve a radical process. This protocol provides a fast and straightforward method for the oxidation of sulfides.