欧前胡素
化学
香豆素
水合物
双糖
蔗糖
立体化学
二维核磁共振波谱
有机化学
高效液相色谱法
作者
Sodik Numonov,Х. М. Бобакулов,Mukhabbat Numonova,Farukh Sharopov,William N. Setzer,Qosimjon Khalilov,Nurmirza Begmatov,Maidina Habasi,Haji Akber Aisa
标识
DOI:10.1080/14786419.2017.1413558
摘要
The new coumarin 1, yuganin A (7-methoxy-8-((1S,2S)-1,2,3-trihydroxy-3-methylbutyl)-2H-chromen-2-one) along with nine known coumarins, heraclenol 3′-O-β-D-glucopyranoside (2), oxypeucedanin hydrate 3′-O-β-D-glucopyranoside (3), heraclenol (4), oxypeucedanin hydrate (5), osthole (6), oxypeucedanin (7), heraclenin (8), isoimperatorin (9), imperatorin (10) and the disaccharide sucrose (11), have been isolated from the roots of Prangos pabularia, and the structures of these isolated compounds were elucidated by spectroscopic means, especially, UV, HR-ESIMS, and 1D and 2D NMR spectroscopy. Furthermore, the anti-melanogenic effect of yuganin A and its inhibitory effect on B16 cells were evaluated. Yuganin A may be useful in the treatment of hyperpigmentation and as a skin-whitening agent in the cosmetics industry.
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