Esophagitis Mimicking Esophageal Cancer on 68Ga-FAPI PET/CT

Abstract A 69-year-old man presented with dysphagia for 6 months. Endoscopic biopsy showed no sign of malignancy, but enhanced chest CT revealed thickening of the esophageal wall, which was considered likely a potential malignancy. The patient subsequently was enrolled in our clinical trial of 68 Ga-FAPI study in tumors. Intense 68 Ga-FAPI activity was noted in the thickened esophagus. However, repeated endoscopic biopsies and relief of symptoms after drug treatment rendered a diagnosis of Candida albicans esophagitis.