Alkylation of Asymmetric Phosphonamidates (Part II)

The stereochemistry of the alkylation of phosphon­amidates 1b is influenced mostly by the chirality of the asymmetric phosphorus atom and not by the chirality of the asymmetric carbon atom. In contrast, the stereochemistry of the alkylation of phos­phonamidates 1c is influenced by a combination of the stereochemistry of the chiral phosphorus atom and the stereochemistry of the chiral carbon atom.