抗氧化剂
氧化应激
过氧化氢酶
超氧化物歧化酶
谷胱甘肽还原酶
毒性
化学
丙二醛
食品科学
谷胱甘肽
脂质过氧化
生物化学
药理学
毒理
生物
酶
谷胱甘肽过氧化物酶
有机化学
作者
Eda Güneş,Erhan Şensoy
出处
期刊:Chemosphere
[Elsevier]
日期:2022-06-01
卷期号:296: 133972-133972
被引量:3
标识
DOI:10.1016/j.chemosphere.2022.133972
摘要
With their increasing use in today's industry, heavy metals cause biochemical and biophysical changes by affecting the control and regulatory systems of living things. Cadmium (Cd), a heavy metal, spreads to the environment through both natural sources and industrial activities. It is taken into the organism through water, food, skin contact or smoke. Systems and organs of living things are directly or indirectly affected by Cd toxicity. Besides their recreational usage, herbal products such as coffee are preferred in alternative medicine because of their antioxidant, anti-inflammatory, anticancer and antidiabetic effects. Turkish coffee (TK) is a drink rich in flavorings, phenolic compounds and antioxidant compounds. The study evaluated the possible antioxidant role of TK against oxidative stress induced by Cadmium acetate (CdA) in the fat tissues of old-young female individuals of Drosophila melanogaster. The female flies were fed with either a standard diet, or CdA (10-30 mg), or TK (2%), or both (CdA + TK) for 3 and 10 days. Following the completion of the feeding period, the amounts of fatbody and oxidative stress markers (oxidative stress index, malondialdehyde), activities of antioxidant enzymes (Glutathione-S-transferase, Catalase, and Superoxide dismutase) and their levels were measured. Fat body lipid droplets were high in the individuals exposed to high concentrations of CdA. It was determined that lipid droplets decreased but did not significantly alter oxidative stress in the individuals treated with TK (p = 0.05). This article may be of help in terms of the use of TK compounds as antioxidants to evaluate their effects in preventing heavy metal accumulation and stress in the aging process.
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