接合作用
门1
生物
癌症研究
PI3K/AKT/mTOR通路
癌症
泛素
细胞生物学
信号转导
泛素连接酶
基因
多发性内分泌肿瘤
遗传学
作者
Junfeng Xu,Zeng Ye,Qifeng Zhuo,Heli Gao,Yi Qin,Xin Lou,Wuhu Zhang,Fei Wang,Yan Wang,Desheng Jing,Guixiong Fan,Yue Zhang,Xuemin Chen,Jie Chen,Xiaowu Xu,Xianjun Yu,Shunrong Ji
出处
期刊：Cancer Research
[American Association for Cancer Research]
日期：2023-03-20
卷期号：83 (13): 2226-2247
被引量：36
标识
DOI：10.1158/0008-5472.can-22-3599
摘要
Identification of neddylation and ubiquitination pathways that regulate MEN1 protein stability provides an opportunity for therapeutic interventions for treating patients with pancreatic neuroendocrine tumors.
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