生物
干细胞生物学
干细胞
细胞生物学
生理学
计算生物学
胚胎
生殖技术
胚胎发生
作者
Benjamin T. Jackson,Lydia W.S. Finley
标识
DOI:10.1016/j.stem.2024.01.003
摘要
Stem cells perform many different functions, each of which requires specific metabolic adaptations. Over the past decades, studies of pluripotent and tissue stem cells have uncovered a range of metabolic preferences and strategies that correlate with or exert control over specific cell states. This review aims to describe the common themes that emerge from the study of stem cell metabolism: (1) metabolic pathways supporting stem cell proliferation, (2) metabolic pathways maintaining stem cell quiescence, (3) metabolic control of cellular stress responses and cell death, (4) metabolic regulation of stem cell identity, and (5) metabolic requirements of the stem cell niche.
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