[Chinese expert consensus on transanal drug administration for constipation (2022 edition )].

Constipation is a clinical symptom. It can be caused by environment, habit, disease and drugs. Chronic constipation is a disease that can occur at any age and its prevalence increases with age. Transanal administration is a common method to treat all kinds of constipation, especially to relieve stool blockage. However, the method and dose of transanal administration vary by age, drug and preparation types of drugs, and the effect of defecation is also quite different. At present, there is no expert consensus to follow in China or abroad. This consensus was convened by Anorectal Branch of Chinese Medical Doctor Association, Colorectal Surgery Group of Branch of Surgery of Chinese Medical Association and Chinese Journal of Gastrointestinal Surgery, to incorporate the latest evidence in China and abroad. This consensus addressed common transanal preparations, principles of administration, and efficacy for constipation. The evidence quality was assessed and the recommendation intensity was graded according to the GRADE system. The consensus aims to help standardize drug selection in practice and guide clinical application.便秘是一种（组）临床症状，可因环境与习惯改变、疾病或药物而引起。慢性便秘是一种疾病，可发生于任何年龄，且随年龄增长患病率不断升高。经肛给药是治疗各种便秘、尤其是缓解粪便堵塞的常用方法，但不同年龄、不同药物和制剂类型以及经肛给药的方法、剂量不同，对促进排粪的效果也有较大的差别。目前，国内外尚无可遵循的临床实践相关专家共识。由中国医师协会肛肠医师分会和中华医学会外科学分会结直肠外科学组牵头，《中华胃肠外科杂志》编辑部召集国内相关领域的专家，结合国内外最新循证医学证据，对便秘常用经肛给药制剂、给药原则与方式进行归纳和整理，依据GRADE系统进行证据质量评估及推荐强度分级，形成《便秘经肛给药治疗中国专家共识（2022版）》，旨在帮助和指导临床实践中药剂的规范和给药方法的选择。.