Curcumin relieves arecoline‐induced oral submucous fibrosis via inhibiting the LTBP2/NF‐κB axis

Submucosal fibrosis (OSF) of the oral cavity is a chronic scarring disease. Arecoline (Are) is the driving factor for the occurrence and deterioration of OSF. Curcumin plays a vital anti-inflammatory role in Are-induced OSF development. However, its potential pharmacological mechanism needs to be elucidated.