医学
冷漠
随机对照试验
萧条(经济学)
生活质量(医疗保健)
物理疗法
物理医学与康复
蒙特利尔认知评估
内科学
疾病
痴呆
宏观经济学
护理部
经济
作者
Silvia Ríos Romenets,Julius Anang,Seyed‐Mohammad Fereshtehnejad,Amélie Pelletier,Ronald B. Postuma
标识
DOI:10.1016/j.ctim.2015.01.015
摘要
To determine effects of Argentine tango on motor and non-motor manifestations of Parkinson's disease. Randomized control trial. Forty patients with idiopathic Parkinson's disease. Movement disorder clinic and dance studio. Two randomized groups: group (N = 18) with 24 partnered tango classes, and control self-directed exercise group (N = 15). The primary outcome was overall motor severity. Secondary outcomes included other motor measures, balance, cognition, fatigue, apathy, depression and quality of life. On the primary intention-to-treat analysis there was no difference in motor severity between groups MDS-UPDRS-3 (1.6 vs.1.2-point reduction, p = 0.85). Patient-rated clinical global impression of change did not differ (p = 0.33), however examiner rating improved in favor of tango (p = 0.02). Mini-BESTest improved in the tango group compared to controls (0.7 ± 2.2 vs. −2.7 ± 5.9, p = 0.032). Among individual items, tango improved in both simple TUG time (−1.3 ± 1.6 s vs. 0.1 ± 2.3, p = 0.042) and TUG Dual Task score (0.4 ± 0.9 vs. −0.2 ± 0.4, p = 0.012), with borderline improvement in walk with pivot turns (0.2 ± 0.5 vs. −0.1 ± 0.5, p = 0.066). MoCa (0.4 ± 1.6 vs. −0.6 ± 1.5, p = 0.080) and FSS (−3.6 ± 10.5 vs. 2.5 ± 6.2, p = 0.057) showed a non-significant trend toward improvement in the tango group. Tango participants found the activity more enjoyable (p < 0.001) and felt more “overall” treatment satisfaction (p < 0.001). We found no significant differences in other outcomes or adverse events. Argentine tango can improve balance, and functional mobility, and may have modest benefits upon cognition and fatigue in Parkinson's disease. These findings must be confirmed in longer-term trials explicitly powered for cognition and fatigue.
科研通智能强力驱动
Strongly Powered by AbleSci AI