Catalytic Enantioselective α‐Oxysulfonylation of Ketones Mediated by Iodoarenes

Abstract The α‐oxysulfonylation of ketones catalysed by enantioenriched iodoarenes using m CPBA as stoichiometric oxidant is reported to give useful synthetic intermediates in good yield and modest enantioselectivity. We believe this to be the first report of an enantioselective organocatalytic reaction involving hypervalent iodine reagents which should open up a new field for enantioselective organocatalysis of oxidation reactions. (© Wiley‐VCH Verlag GmbH & Co. KGaA, 69451 Weinheim, Germany, 2008)