Omeprazole Versus High-Dose Ranitidine in Mild Gastroesophageal Reflux Disease: Short- and Long-Term Treatment

Omeprazole 20 mg daily is superior to high-dose ranitidine in the symptomatic treatment of reflux esophagitis grade I and II. Furthermore, omeprazole at half the standard dose is more effective than ranitidine in a standard dose in keeping patients in remission for a period of 12 months.