It is my pleasure to serve as guest editor of this issue of Seminars in Plastic Surgery-Oculofacial Plastic and Reconstructive Surgery. Periorbital and orbital procedures are common operations performed by plastic surgeons. Although these procedures have only a few core principles, it is important for the plastic surgeon to apply these principles in a safe fashion. In my experience, it is the potential complications that make these procedures challenging. In this issue of Seminars in Plastic Surgery, we present articles that highlight techniques in periorbital and orbital surgery.