Studies on Alkanolamines. II

By heating phenylacetylcarbinol and methylbenzoylcarbinol, or their acetates, with secondary amines, such as dimethylamine, diethylamine, benzylmethylamine, piperidine, or N-methylpiperazine, in a sealed tube at 150-180°, α-sec-aminopropiophenones were obtained in 10-44% yield. The objective was also attained by treating a few other acetates with secondary amines. From the results obtained, the foregoing reaction may be termed as the Viogt reaction.