Inhibition of the Molecular Chaperone Heat Shock Protein 90 in Cancer: Consequences for the Regulation of Survival Signaling and Induction of Cell Death
作者
Paul A. Clarke,Marissa Powers,Paul Workman
标识
DOI:10.1002/9783527619665.ch37
摘要
This chapter contains sections titled: Introduction Hsp90- An Exciting Anticancer Drug Target Molecular and Cellular Consequences of Hsp90 Inhibition Hsp90 Client Depletion and Apoptosis Hsp90 and the Apoptotic Machinery Regulation of Apoptosis by Other Heat Shock Proteins Induced Following Hsp90 Inhibition Summary