生物
油菜
十字花科
基因组
单核苷酸多态性
SNP阵列
芸苔属
基因组学
计算生物学
核苷酸多型性
SNP公司
遗传学
SNP基因分型
连锁不平衡
植物
基因
基因型
作者
Su Yang,Rafaqat Ali Gill,Qamar U. Zaman,Zaid Ulhassan,Weijun Zhou
标识
DOI:10.1016/j.jbiotec.2020.09.018
摘要
The genus Brassica, family Brassicaceae (Cruciferae), comprises many important species of oil crops, vegetables and medicinal plants including B. rapa, B. oleracea, B. nigra, B. napus, B. juncea, B. carinata. Genomic researches in Brassica species is constrained by polyploidization, mainly due to its complicated genomic structure. However, rapid development of methods for detecting single nucleotide polymorphisms (SNP), such as next generation sequencing and SNP microarray, has accelerated release of reference Brassica species genomes as well as discovery of large numbers and genome-wide SNPs, thus intensifying forward genetics in this genus. In this review, we summarize biological characteristics, classification and various methods for detecting SNPs, focusing on high-throughput techniques. Moreover, we describe the pivotal roles of SNPs in genetic diversity, linkage map construction and QTL mapping, comparative genomics, linkage disequilibrium and genome-wide association studies. These insights are expected to deepen our understanding and guide further advancements in Brassica species research.
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