Clinical analysis on relative factors of hepatoma early diagnosis in 300 cases of youth hepatitis and liver cirrhosis

Objective To investigate the factors associated with hepatoma early diagnosis in 300 cases of youth hepatitis and liver cirrhosis.Methods The case history,auxiliary examination and relative risk(RR) were done in 300 cases of youth hepatitis and liver cirrhosis aged 18 to 40 years old.Results The total proportion of male to female was 3.76 to 1.The cases of liver cancer and virus hepatitis complicated with liver cirrhosis acounted for 72% and 63% respectively.The RR of hepatitis and liver cirrhosis developing to hepatoma were 26.78 and 2.27 respectively.The AFP positive rate in liver cancer patients was 68.36%;the patients with AFP above 400 ng/ml accounted for 44.89%.HBV infection marker decreased progressively with the development of hepatitis,hepatic cirrhosis and hepatoma.Conclusion The male youth with virus hepatitis and liver cirrhosis are high-risk poputlation of liver cancer.The patients with familial hepatoma and history of other cancer have the higer rate of RR.Positive AFP has the impontant value in clinic for early diagnosis of liver cancer.