OBJECTIVE: To provide reference material for the adaptation of the study on Chinese phytomedicine to the global research and development of phytomedicine. METHOD: Based on research experiences, some problems, such as resources, quality and effective components of Chinese phytomedicine, were discussed, and some suggestions were put forward. RESULT AND CONCLUSION: Facing the opportunity brought by the global research and development of phytomedicine, it is essential to solve several main problems for the global recognition of Chinese phytomedicine.