The dispersion process of nano TiO_2 in water medium with physical and chemical methods was studied using sedimentometric method.The results indicated that among three dispersion methods the best dispersion effect is the ultrasonic dispersion;the second one is the dispersion with adding SDBS(Sodium Dodecyl Benzene Sulfonate) in water;the last one is electromotive stirring dispersion.For the electromotive stirring dispersion the best effect obtained is stirring about 90 min and using higher rotating speed.For ultrasonic dispersion the best effect is obtained with ultrasonic voltage of 180 V and processing for 70 minutes.For dispersion with SDBS the best effect is obtained with addition of SDBS 12.0 g/L.