When is antibiotic therapy necessary for patients with infections in hard-to-heal wounds?

Journal of Wound CareVol. 32, No. 1 EditorialWhen is antibiotic therapy necessary for patients with infections in hard-to-heal wounds?Ojan Assadian, Karen J Ousey, Leigh Fleming, Rakesh Mishra, Joanna Blackburn, Fabiola SigmundOjan AssadianMedical Director, Regional Hospital Neustadt, Vienna, Austria; Institute of Skin Integrity and Infection Prevention, University of Huddersfield, UKSearch for more papers by this author, Karen J OuseyProfessor and Director for the Institute of Skin Integrity and Infection Prevention, University of Huddersfield, UKSearch for more papers by this author, Leigh FlemingReader, Director of Home Recruitment, School of Computing and Engineering, Institute of Skin Integrity and Infection Prevention, University of Huddersfield, UKSearch for more papers by this author, Rakesh MishraProfessor and Co-director for the Centre for Thermofluids, Energy Systems and High Performance Computing, School of Computing and Engineering, Institute of Skin Integrity and Infection Prevention, University of Huddersfield, UKSearch for more papers by this author, Joanna BlackburnResearch Fellow, Institute of Skin Integrity and Infection Prevention, University of Huddersfield, UKSearch for more papers by this author, Fabiola SigmundClinical Research Coordinator, Regional Hospital Wiener Neustadt, AustriaSearch for more papers by this authorOjan Assadian; Karen J Ousey; Leigh Fleming; Rakesh Mishra; Joanna Blackburn; Fabiola SigmundPublished Online:11 Jan 2023https://doi.org/10.12968/jowc.2023.32.1.3AboutSectionsView articleView Full TextPDF/EPUB ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareShare onFacebookTwitterLinked InEmail View article References 1 International Wound Infection Institute (IWII) Wound infection in clinical practice. Wounds International. 2022. https://woundinfection-institute.com/resources/ (accessed 7 December 2022) Google Scholar2 Kramer A, Dissemond J, Kim S et al.. Consensus on wound antisepsis: update 2018. Skin Pharmacol Physiol 2018; 31(1):28–58. https://doi.org/10.1159/000481545 Crossref, Medline, Google Scholar3 Müller G, Kramer A. Biocompatibility index of antiseptic agents by parallel assessment of antimicrobial activity and cellular cytotoxicity. J Antimicrob Chemother 2008; 61(6):1281–1287. https://doi.org/10.1093/jac/dkn125 Crossref, Medline, Google Scholar4 Roberts CD, Leaper DJ, Assadian O. The role of topical antiseptic agents within antimicrobial stewardship strategies for prevention and treatment of surgical site and chronic open wound infection. Adv Wound Care (New Rochelle) 2017; 6(2):63–71. https://doi.org/10.1089/wound.2016.0701 Crossref, Medline, Google Scholar5 Dissemond J, Assadian O, Gerber V et al.. Classification of wounds at risk and their antimicrobial treatment with polihexanide: a practice-oriented expert recommendation. Skin Pharmacol Physiol 2011; 24(5):245–255 Crossref, Medline, Google Scholar6 World Union of Wound Healing Societies (WUWHS). Principles of best practice: wound infection in clinical practice. An international consensus. Int Wound J 2008; 5(suppl 3):iii–11. https://doi.org/10.1111/j.1742-481x.2008.00488.x Crossref, Google Scholar7 Kingston D, Seal DV. Current hypotheses on synergistic microbial gangrene. Br J Surg 1990; 77(3):260–264. https://doi.org/10.1002/bjs.1800770309 Crossref, Medline, Google Scholar8 Itani KMF, Shorr AF. FDA Guidance for ABSSSI trials: implications for conducting and interpreting clinical trials. Clin Infect Dis 2014; 58(Suppl 10):S4–S9. https://doi.org/10.1093/cid/cit612 Crossref, Medline, Google Scholar9 Bodmann KF, Grabein B, Kresken M. S2k guideline ‘Calculated parenteral initial treatment of bacterial infections in adults – update 2018’, 2nd updated version: Foreword. GMS Infect Dis 2020; 8: Doc20. https://doi.org/10.3205/id000064 Medline, Google Scholar FiguresReferencesRelatedDetails 2 January 2023Volume 32Issue 1ISSN (print): 0969-0700ISSN (online): 2052-2916 Metrics History Published online 11 January 2023 Published in print 2 January 2023 Information© MA Healthcare LimitedPDF download