Analysis of frailty determinants in chronic stroke patients

In patients with chronic stroke, frailty, as measured with the EFS, is best predicted by age and by the stroke-related impaired self-efficacy. Interestingly, the latter is a stronger frailty predictor, especially in younger patients. These findings indicate that both physiological and disease-related functional declines contribute to the development of frailty. However, additional longitudinal studies are necessary to validate the causal association and to account for potential confounding factors like depression or social support.