体内分布
医学
胆囊
成纤维细胞活化蛋白
病理
病理生理学
核医学
内科学
癌症
体外
生物化学
化学
作者
Hossein Behnammanesh,Abtin Doroudinia,Mohadeseh Bayat,Mehrdad Bakhshayeshkaram,Babak Salimi,Marzieh Nejabat,Payam Mehrian
出处
期刊:Clinical Nuclear Medicine
[Ovid Technologies (Wolters Kluwer)]
日期:2023-11-16
卷期号:49 (1): e40-e41
标识
DOI:10.1097/rlu.0000000000004955
摘要
Abstract Radiolabeled fibroblast activation protein inhibitors (FAPIs) have been extensively used in different types of cancers, although not yet FDA approved. Normal patterns of FAPI biodistribution have been investigated, and it is known that FAPI is expressed in nonmalignant pathophysiological lesions, characterized by tissue remodeling such as atherosclerosis, arthritis, and scar/fibrotic tissues. In this interesting image, we are presenting the accumulation of 68 Ga-FAPI in the gallbladder. This finding could be related to a normal distribution of the radiotracer as a physiologic finding. This is a potentially important finding as FAPI may be used as theragnostic agent in the future.
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