化学
光动力疗法
特里斯
程序性细胞死亡
联吡啶
光敏剂
2,2'-联吡啶
立体化学
癌症研究
细胞凋亡
组合化学
药物化学
光化学
生物化学
有机化学
晶体结构
生物
作者
Hongwei Zheng,K. Wang,Dongliang Ji,Xiao Liu,Chen Wang,Yangyang Jiang,Zihan Jia,Biao Xiong,Yong Ling,Jiefei Miao
标识
DOI：10.1016/j.ejmech.2024.116909
摘要
Ru(II) complexes have attracted attention as photosensitizers for their promising photodynamic properties. Herein, novel tris-bipyridine based Ru(II) complexes (6a-e) were synthesized by introducing saturated heterocycles to improve photodynamic properties and lipid-water partition coefficients. Among them, 6d demonstrated significant phototoxicity towards three cancer cells, with IC
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