骨肉瘤
甲氨蝶呤
恶性肿瘤
癌症研究
组蛋白
医学
生物
内科学
遗传学
DNA
作者
YUSUKE AOKI,Yutaro Kubota,NORIYUKI MASAKI,Koya Obara,Yasunori Tome,Michael Bouvet,Kotaro Nishida,Robert M. Hoffman
出处
期刊:Anticancer Research
[International Institute of Anticancer Research (IIAR) Conferences 1997. Athens, Greece. Abstracts]
日期:2024-09-30
卷期号:44 (10): 4213-4218
标识
DOI:10.21873/anticanres.17251
摘要
Over-expression of histone H3K9me3 and H3K27me3 marks may be related to super-MTX resistance and to the loss of malignancy of super MTX-resistant osteosarcoma cells due to the fundamental relationship of methylation and cancer.
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