mTORC2, a Novel “Twist” on the Epithelial Sodium Channel (ENaC)

1Division of Nephrology and Hypertension, Department of Medicine, Oregon Health and Science University, Portland, Oregon 2Oregon Clinical and Translational Research Institute, Oregon Health and Science University, Portland, Oregon 3VA Portland Health Care System, Portland, Oregon Correspondence: Dr. David H. Ellison, Oregon Clinical and Translational Research Institute, Oregon Health and Science University, 3181 SW Sam Jackson Park Road, Portland, OR 97239. Email: [email protected] See related article, “Potassium Activates mTORC2-dependent SGK1 Phosphorylation to Stimulate Epithelial Sodium Channel: Role in Rapid Renal Responses to Dietary Potassium,” on pages 1019–1038. Published online ahead of print. Publication date available at www.jasn.org.