化学
过氧化氢
降级(电信)
四环素
质谱法
催化作用
氧化还原
四环素类抗生素
比色法
色谱法
组合化学
有机化学
生物化学
抗生素
计算机科学
电信
作者
Weizheng Wang,Yaoqi Yin,Sundaram Gunasekaran
出处
期刊:Food Chemistry
[Elsevier]
日期:2023-11-01
卷期号:426: 136607-136607
被引量:3
标识
DOI:10.1016/j.foodchem.2023.136607
摘要
Tetracycline (TC) is a broad-spectrum antibiotic that can enter and accumulate in the human body via the food chain. Even in small concentrations, TC can cause several malignant health effects. We developed a system to simultaneously degrade the presence of TC in food matrices using titanium carbide MXene (FL-Ti3C2Tx). The FL-Ti3C2Tx exhibited biocatalytic property that activates hydrogen peroxide (H2O2) molecules in 3, 3′, 5, 5′-tetramethylbenzidine (TMB environment. During the FL-Ti3C2Tx reaction, the catalytic products released turn the color of the H2O2/TMB system bluish-green. However, when TC is present, the bluish-green color does not appear. Via quadrupole time-of-flight mass spectrometry, we found that the TC is degraded by FL-Ti3C2Tx / H2O2 in preference to H2O2/TMB redox reaction, which intervenes in the color change. Hence, we developed a colorimetric assay to detect TC with a LOD of 615.38 nM and proposed two TC degradation pathways that facilitate the highly sensitive colorimetric bioassay.
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