[A study on the burden of myocarditis in China in 1990 and 2019].

Objective: To investigate Chinese myocarditis burden and trends in 1990 and 2019. Methods: Based on the Global Burden of Disease (GBD) 2019 data, the number of patients, the number of new cases, the number of deaths, the disability-adjusted life years (DALYs), as well as the morbidity, mortality, DALYs rate and their age-standardized rates were used to analyze the trend and the burden of myocarditis in the Chinese population in 1990 and 2019. Results: In 2019, the number of patients, the number of new cases and the number of deaths with myocarditis in China were 234 900, 275 100 and 13 100 respectively, increasing by 85.62%, 47.51% and 50.22% compared with 1990. The age-standardized incidence and mortality were 16.94/100 000 and 0.92/100 000, respectively. Compared with 1990, the age-standardized incidence in 2019 decreased by 6.06%, and the mortality decreased by 16.04% respectively. The age-standardized incidence and mortality of Chinese male patients with myocarditis were higher than that of female. Compared with 1990, the age group with the largest incidence and mortality of myocarditis in China in 2019 all shifted to the elder group. And, DALYs and age-normalized DALYs due to myocarditis in China showed a decreasing trend in 2019, from 458 600 and 42.51/100 000 in 1990 to 341 300 and 25.39/100 000 in 2019, respectively. The rate of DALYs and age-standardized DALYs in male patients was always higher than female. Conclusions: Compared with 1990, the overall burden of myocarditis in China showed a downward trend in 2019, and the burden of myocarditis in male patients was higher than female. More attention should be paid to the burden of myocarditis in Chinese elderly population.目的： 分析1990年和2019年中国人群心肌炎疾病负担及其变化趋势。 方法： 基于全球疾病负担（GBD）1990年和2019年数据，采用患病人数、新发病例人数、死亡人数、伤残调整寿命年（DALYs）以及年龄标化发病率、病死率、DALYs率等指标，分析中国人群罹患心肌炎的疾病负担变化趋势。 结果： 2019年中国心肌炎患病人数、新发病例人数及死亡人数分别为23.49万、27.51万、1.31万例，相较于1990年分别增长了85.62%、47.51%和50.22%。发病率和病死率分别为16.94/10万、0.92/10万。相较于1990年分别下降了6.06%和16.04%。中国男性心肌炎患者的年龄标化发病率及病死率均高于女性。与1990年相比，2019年中国人群心肌炎患病人数、发病人数、死亡人数最多的年龄段均向高龄人群转变，且因心肌炎导致的DALYs和年龄标化DALYs率均呈下降趋势，分别由1990年的45.86万人年和42.51/10万降至2019年的34.13万人年和25.39/10万，男性患者的DALYs和年龄标化DALYs率总是高于女性。 结论： 与1990年比较，2019年中国心肌炎的疾病负担总体呈下降趋势，男性人群心肌炎疾病负担高于女性，且中国老年人群的心肌炎疾病负担需要给予更多的关注。.