作者
Carlota Fernández Prendes,Barbara Rantner,Tarek Hamwi,Jan Stana,Valery L. Feigin,Konstantinos Stavroulakis,Nikolaos Tsilimparis,Carlota Fernández Prendes,Barbara Rantner,Tarek Hamwi,Jan Stana,Prof Valery L Feigin,Konstantinos Stavroulakis,Nikolaos Tsilimparis,Prof Victor Aboyans,Rufus Akinyemi,Pamela Salman,Anton A Artamonov,Avinash Aujayeb,Marzia Baldereschi,Sanjay Basu,Prof Yannick Béjot,Luis Belo,Derrick Bennett,Akshaya Srikanth Bhagavathula,Boris Bikbov,Philip Brenner,Florentino Luciano Caetano dos Santos,Pablo Carrero,P Carvalho,P Catapano,Periklis Charalampous,Peter Christensen,Sheng‐Chia Chung,P. Cortesi,Vera Marisa Costa,Małgorzata Cygańska,Emanuele D’Amico,Kairat Davletov,Клара Докова,Abdel Douiri,Adeniyi Francis Fagbamigbe,Florian Fischer,Nermin Ghith,Simona Giampaoli,Paula Gill,Elena V. Gnedovskaya,Rasmus Havmoeller,Sorin Hostiuc,Prof Ivo Iavicoli,Predrag Ilić,Prof Gaetano Isola,Jacek Jerzy Jóźwiak,Mikk Jürisson,Gbenga A Kayode,Moien AB Khan,Prof Khaled Khatab,Phyllis Kisa,Pirjo-Riitta Kivimäki,Ai Koyanagi,Mukhtar Kulimbet,Dian Kusuma,P. Di Vecchia,Ben Lacey,Prof Tea Lallukka,Prof Stefan Lorkowski,Prof Azeem Majeed,Plinio Ferreira Mantovani,Giampiero Mazzaglia,Alexios-Fotios A Mentis,Tuomo J Meretoja,Junmei Miao Jonasson,Andreea Mirică,Prof Erkin M Mirrakhimov,Shafiu Mohammed,Mariam Molokhia,Lorenzo Monasta,Prof Ute Mons,Jakub Morze,Ruxandra Irina Negoi,Prof Bo Norrving,Prof Bogdan Oancea,Rónán Ó’Caoimh,Hans Orru,Alicia Padrón‐Monedero,Paolo Pedersini,Norberto Perico,Р. В. Полибин,Suzanne Polinder,Alberto Raggi,Prof Salman Rawaf,Prof Giuseppe Remuzzi,Michele Romoli,Paul Sacco,Prof Mohammad Reza Saeb,João Vasco Santos,Prof Milena M Santric-Milicevic,Anna Aleksandrovna Skryabina,Lee Smıth,Antonina V Starodubova,Aleksandar Stevanović,Prof Saverio Stranges,Yvonne Teuschl,Roman Topór-Mądry,Mathilde Touvier,Marcos Roberto Tovani‐Palone,Brigid Unim,Prof Tommi Juhani Vasankari,Victor Volovici,Hatem Wafa,Yanzhong Wang,Ronny Westerman,Pam Wolfe,Metin Yeşiltepe,Aurora Zanghì,Prof Mikhail Sergeevich Zastrozhin
摘要
BACKGROUND: While most European Regions perform well in global comparisons, large discrepancies within stroke epidemiological parameters exist across Europe. The objective of this analysis was to evaluate the stroke burden across European regions and countries in 2019 and its difference to 2010. METHODS: The GBD 2019 analytical tools were used to evaluate regional and country-specific estimates of incidence, prevalence, deaths, and disability-adjusted life years of stroke for the European Region as defined by the World Health Organization, with its 53 member countries (EU-53) and for European Union as defined in 2019, with its 28 member countries (EU-28), between 2010 and 2019. Results were analyzed at a regional, subregional, and country level. RESULTS: In EU-53, the absolute number of incident and prevalent strokes increased by 2% (uncertainty interval [UI], 0%–4%), from 1 767 280 to 1 802 559 new cases, and by 4% (UI, 3%–5%) between 2010 and 2019, respectively. In EU-28, the absolute number of prevalent strokes and stroke-related deaths increased by 4% (UI, 2%–5%) and by 6% (UI, 1%–10%), respectively. All-stroke age-standardized mortality rates, however, decreased by 18% (UI, −22% to −14%), from 82 to 67 per 100 000 people in the EU-53, and by 15% (UI, −18% to −11%), from 49.3 to 42.0 per 100 000 people in EU-28. Despite most countries presenting reductions in age-adjusted incidence, prevalence, mortality, and disability-adjusted life year rates, these rates remained 1.4×, 1.2×, 1.6×, and 1.7× higher in EU-53 in comparison to the EU-28. CONCLUSIONS: EU-53 showed a 2% increase in incident strokes, while they remained stable in EU-28. Age-standardized rates were consistently lower for all-stroke burden parameters in EU-28 in comparison to EU-53, and huge discrepancies in incidence, prevalence, mortality, and disability-adjusted life-year rates were observed between individual countries.