重新调整用途
2019年冠状病毒病(COVID-19)
严重急性呼吸综合征冠状病毒2型(SARS-CoV-2)
计算机科学
纳米技术
风险分析(工程)
2019-20冠状病毒爆发
数据科学
工程类
医学
病毒学
传染病(医学专业)
疾病
材料科学
废物管理
病理
爆发
作者
Nunzio Iraci,Carmelo Corsaro,Salvatore V. Giofrè,G. Neri,A. M. Mezzasalma,Martina Vacalebre,Antonio Speciale,Antonella Saija,Francesco Cimino,Enza Fazio
出处
期刊:Biomolecules
[MDPI AG]
日期:2022-07-30
卷期号:12 (8): 1060-1060
被引量:2
摘要
The last few years have increasingly emphasized the need to develop new active antiviral products obtained from artificial synthesis processes using nanomaterials, but also derived from natural matrices. At the same time, advanced computational approaches have found themselves fundamental in the repurposing of active therapeutics or for reducing the very long developing phases of new drugs discovery, which represents a real limitation, especially in the case of pandemics. The first part of the review is focused on the most innovative nanomaterials promising both in the field of therapeutic agents, as well as measures to control virus spread (i.e., innovative antiviral textiles). The second part of the review aims to show how computer-aided technologies can allow us to identify, in a rapid and therefore constantly updated way, plant-derived molecules (i.e., those included in terpenoids) potentially able to efficiently interact with SARS-CoV-2 cell penetration pathways.
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