硼烷
化学
磷化氢
吡那考
试剂
还原剂
硫化物
四氢呋喃
组合化学
光化学
有机化学
无机化学
催化作用
溶剂
作者
Cei Provis-Evans,Emma Anna Carolina Emanuelsson,Ruth L. Webster
标识
DOI:10.1002/adsc.201800723
摘要
Abstract A rapid method for the reduction of secondary phosphine oxides under mild conditions has been developed, allowing simple isolation of the corresponding free phosphines. The methodology involves the use of pinacol borane (HBpin) to effect the reduction while circumventing the formation of a phosphine borane adduct, as is usually the case with various other commonly used borane reducing agents such as borane tetrahydrofuran complex (BH 3 ⋅THF) and borane dimethyl sulfide complex (BH 3 ⋅SMe 2 ). In addition, this methodology requires only a small excess of reducing agent and therefore compares favourably not just with other borane reductants that do not require a metal co‐catalyst, but also with silane and aluminium based reagents. magnified image
科研通智能强力驱动
Strongly Powered by AbleSci AI