阿兹平
化学
微波辐射
戒指(化学)
组合化学
范围(计算机科学)
有机化学
催化作用
计算机科学
程序设计语言
作者
Manvinder Kaur,Sonali Garg,Dharambeer Singh Malhi,Harvinder Singh Sohal
标识
DOI:10.2174/1385272825999210104222338
摘要
Seven membered heterocyclic Azepine and its derivatives have great pharmacological and therapeutic implications. In this review, the literature of the last fifty years has been exploited for the synthesis, reaction, and biological properties of these seven-member heterocyclic compounds. Most of the mechanisms involved the ring expansion of either five or six-membered compounds using various methods such as thermally, photo-chemically, and microwave irradiation. The systematically designed schemes involve the synthesis of different derivatives of azepine, azepinone, azepane, etc., using similar moieties by various researchers. However, there is much work yet to be done in the biological section, as it is not explored and reported in the literature; therefore, N-containing seven-membered heterocycles still have much scope for the researchers.
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