The compared orthogonal experiments on the conditions of solvent extraction and stripping of indium with P204-sulphonating kerosene and P204-Cyanex 923-sulphonating kerosene were carried out under the high latitude.The results indicated that the solvent extraction of indium was not affected and the extraction of Fe in organic phase was inhibited when the concentration of Cyanex 923 was maintained with a proper ratio.The solution of 3 mol/L HCl+1 mol/L ZnCl2 was an excellent stripping agent for P204-Cyanex 923-sulphonating kerosene.