成核
冰核
材料科学
纤维素
化学工程
Crystal(编程语言)
生物物理学
冰晶
化学
纳米晶
纳米技术
化学物理
有机化学
生物
地理
气象学
工程类
程序设计语言
计算机科学
作者
Yi Hou,Xuyang Sun,Mengjia Dou,Chennan Lu,Jing Liu,Wei Rao
出处
期刊:Nano Letters
[American Chemical Society]
日期:2021-04-05
卷期号:21 (11): 4868-4877
被引量:6
标识
DOI:10.1021/acs.nanolett.1c00514
摘要
Ice nucleators are of crucial and important implications in various fields including chemistry, climate, agriculture, and cryobiology. However, the complicated extract and biocompatibility of ice nucleators remain unresolved, and the mechanism of ice nucleation remains largely unknown. Herein, we show that natural nanocrystalline cellulose materials possess special properties to enhance ice nucleation and facilitate needle-like ice crystal growth. We reveal the molecular level mechanism that the efficient exposure of cellulose hydroxyl groups on (−110) surface leads to faster nucleation of water. We further design chitosan-decorated cellulose nanocrystals to accomplish molecular cryoablation in CD 44 high-expression cells; the cell viability shows more than ∼10 times decrease compared to cryoablation alone and does not show evident systematic toxicity. Collectively, our findings also offer improved knowledge in molecular level ice nucleation, which may benefit multiple research communities and disciplines.
科研通智能强力驱动
Strongly Powered by AbleSci AI