Enriched biological and mechanical properties of boron doped SiO2-CaO-Na2O-P2O5 bioactive glass ceramics (BGC)

Abstract This study emphasizes on the effect and consequence of boron substitution, concerning physical and biological properties of SiO2-Na2O-CaO-P2O5-B2O3 glass ceramics. The temperature of the glass transition and crystallization was decreased slightly due to high degree of boron incorporation. The boron substitution was increased from 0 to 10% by proportionately decreasing calcium which alters glass structure and transformation occurs from sodium calcium silicate to sodium boron silicate phase by the ionic exchange between calcium and boron . This intensifies the compressive strength of glass ceramics to 70 MPa and increases the conversion rate of glass ceramics to tricalcium phosphate (TCP) in a physiological fluid. The influence of boron on glass ceramic has been studied to increase its bioactivity, efficiency and mechanical properties for the application of bone tissue engineering. In addition, its antimicrobial properties reveal a potential antibacterial effect on gram negative (E. coli) and gram positive bacteria (S. aureus).