自动化
计算生物学
蛋白质微阵列
鉴定(生物学)
稳健性(进化)
计算机科学
基因芯片分析
微阵列
生化工程
生物信息学
生物
工程类
机械工程
基因
植物
生物化学
基因表达
作者
Dieter Stoll,Jutta Bachmann,Markus F. Templin,Thomas Joos
出处
期刊:Drug Discovery Today: Targets
[Elsevier]
日期:2004-02-01
卷期号:3 (1): 24-31
被引量:26
标识
DOI:10.1016/s1741-8372(04)02400-4
摘要
Protein microarray technology allows the simultaneous determination of a large variety of parameters from a minute amount of sample within a single experiment. Assay systems based on this technology are currently used for the identification, quantitation and functional analysis of proteins that are of interest for proteomic research in basic and applied biology and for diagnostic applications. Such novel assays are also of major interest for the pharmaceutical industry, focusing on the identification of biomarkers and the validation of potential target molecules. Sensitivity, reproducibility, robustness and automation have to be demonstrated before this technology will be suitable for high-throughput applications.
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