化学
亚胺
醛
立体选择性
对映选择合成
氢键
苯
共振(粒子物理)
立体化学
双键
有机化学
分子
催化作用
粒子物理学
物理
作者
Kwan Mook Kim,Hyun-Jung Park,Hae-Jo Kim,Jik Chin,Wonwoo Nam
出处
期刊:Organic Letters
[American Chemical Society]
日期:2005-07-07
卷期号:7 (16): 3525-3527
被引量:46
摘要
A chiral aldehyde with three H-bond donating groups (2) has been synthesized. This aldehyde binds a variety of chiral 1,2-amino alcohols in benzene with the same sense of stereoselectivity. Computational and experimental data indicate that one imine bond, one resonance-assisted H-bond to the imine nitrogen, and two H-bonds to the alcoholic oxygen all play an important role in the stereoselective recognition.
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