Side effects of chlorhexidine mouth washes

abstract – The side effects of chlorhexidine mouth washes have been evaluated in a group of 50 soldiers during a period of 4 months. Previous publications have shown the effects on plaque formation and gingival conditions. The present paper discusses unfavorable side effects. When rinsing with 0.2 and 0.1 % chlorhexidine gluconate and acetate, some desquamations and soreness in the oral mucosa were observed. Twelve per cent of the tooth surfaces and 62 % of the silicate fillings were discolored, while 36 % of the test persons developed discolored tongues in the experimental period. Because of the side effects, there. are some objections to uncritical use of chlorhexidine in preventive dentistry. A close control is necessary; and until more information is gained, the use of chlorhexidine mouth washes is recommended for short periods only. Other methods of application must be studied.