A bioinspired photoenzymatic cascade enabled by a bifunctional arylformamidase for efficient synthesis of l -kynurenine derivatives

A bioinspired one-pot one-step photoenzymatic cascade integrating a metal-free photocatalyst and an engineered bifunctional arylformidase directly convert l -Trp and its esters into l -Kyn under mild conditions with excellent green metrics evaluation.