医学
随机对照试验
生活质量(医疗保健)
心理干预
物理疗法
置信区间
质量调整寿命年
毒物控制
经济评价
伤害预防
职业安全与健康
前瞻性队列研究
成本效益分析
医疗保健
自杀预防
日常生活活动
成本效益
防坠落
物理医学与康复
人为因素与人体工程学
梅德林
成本效益分析
老年学
作者
Mohammad Jobair Khan,Kenneth N. K. Fong,Thomson W. L. Wong,William Wai-nam Tsang,Wai-chi Chan,Cynthia Chen,Stanley John Winser
标识
DOI:10.1123/jpah.2025-0252
摘要
BACKGROUND: Uncertainty exists among health practitioners and policymakers regarding the adoption of cost-effective interventions to prevent falls in community-dwelling older adults. This study compares cost-effectiveness of self-administered dual-task training (sDT) with self-administered single-task training (sST) for fall prevention. METHODS: This prospective randomized controlled trial included 216 older adults aged over 65 years with a previous fall history. Assessments were conducted at baseline, postintervention, and a 6-month follow-up, and the study outcomes were measured using fall frequency and quality of life. The association between treatments and prospective fall-related direct medical costs was assessed using 2-part models. A half-cycle corrected Markov model estimated cost-effectiveness over 10 years and calculated incremental cost-effectiveness ratios and quality-adjusted life years. The strength of the findings was evaluated using deterministic and probabilistic sensitivity analyses. RESULTS: Participants of the sDT group had significantly lower hospitalization costs (mean = US$34, coefficient [coef.] = -169,262; 95% confidence interval, -173,614.7 to -164,910; P < .0001), compared with the sST group (mean = $211.31; coef. = 24,724.36). Compared with sST, sDT meets the highly cost-effective healthcare approach criterion with an incremental cost-effectiveness ratio of -$737,347. Base-case analysis reported the cost (sDT = $1995, sST = $2692; difference: -$696) saving of sDT interventions and improvement in quality-adjusted life years (sDT = 8.67, sST = 8.39; difference: -0.29) due to practicing sDT with a health benefit of 0.09 quality-adjusted life years per person per year. CONCLUSION: Findings of this cost-effective analysis suggest that sDT improves quality of life for participants and reduces healthcare costs due to a lower fall incidence and hospitalization, meeting the cost-effective threshold criteria from a Hong Kong healthcare perspective.
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