Gadolinium Retention in Pediatric Bone: Linear versus Macrocyclic MRI Contrast Agents

< .001). Conclusion Exposure to the linear agent gadobenate at MRI was associated with higher gadolinium concentrations in bone tissue than no GBCA exposure or exposure to the macrocyclic agent gadoterate; trace gadolinium in the bone tissue of controls may reflect environmental exposure. Clinical trial registration no. NCT03337594 © RSNA, 2026