医学
DNA甲基化
表观基因组
内科学
CpG站点
表观遗传学
肿瘤坏死因子α
肿瘤科
队列
甲基化
遗传学
生物
基因
基因表达
作者
Stella Aslibekyan,Golareh Agha,Elena Colicino,Anh N.,Jari Lahti,Symen Ligthart,Riccardo E. Marioni,Carola Marzi,Michael Mendelson,Toshiko Tanaka,Matthias Wielscher,Devin Absher,Luigi Ferrucci,Oscar H. Franco,Christian Gieger,Harald Grallert,Dena Hernández,Tianxiao Huan,Stella Iurato,Roby Joehanes
出处
期刊:JAMA Cardiology
[American Medical Association]
日期:2018-04-04
卷期号:3 (6): 463-463
被引量:42
标识
DOI:10.1001/jamacardio.2018.0510
摘要
We identified and replicated novel epigenetic correlates of circulating TNF-α concentration in blood samples and linked these loci to coronary heart disease risk, opening opportunities for validation and therapeutic applications.
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