蛋白酶体
抗原处理
抗原
细胞生物学
生物
计算生物学
化学
免疫学
主要组织相容性复合体
MHC I级
摘要
The proteasome is an essential part of our immune surveillance mechanisms: by generating peptides from intracellular antigens it provides peptides that are then 'presented' to T cells. But proteasomes ? the waste-disposal units of the cell ? typically do not generate peptides for antigen presentation with high efficiency. How, then, does the proteasome adapt to serve the immune system well?
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