丝素
生物相容性
自愈水凝胶
伤口愈合
伤口敷料
化学
抗菌活性
抗菌剂
丝绸
高分子化学
材料科学
细菌
复合材料
有机化学
外科
医学
生物
遗传学
作者
Fan Zhang,Chuanjin Yin,Xueju Qi,Chenglin Guo,Xiaochen Wu
标识
DOI:10.1002/mabi.202100407
摘要
Antibacterial hydrogels are intensively studied as wound dressings. Silk fibroin (SF) is chemical crosslinked to glycyrrhizic acid (GA) and silver to fabricate a hydrogel dressing with both antibacterial and anti-inflammatory properties. The SF/Ag/GA hydrogel exhibits high water content with acceptable mechanical properties, combines the good biocompatibility and biodegradability of SF, the antibacterial activity of silver, and the anti-inflammatory property of GA, capable to promote tissue regeneration during wound healing process, offering great potential as an alternative for wound dressings.
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