再生(生物学)
再生医学
医学
脊髓损伤
中枢神经系统
神经科学
干细胞
人体
脊髓
生物信息学
重症监护医学
生物
解剖
内科学
遗传学
细胞生物学
作者
Nikhil N. Verma,Alex Fazioli,Paige Matijasich
出处
期刊:Regenerative Medicine
[Future Medicine]
日期:2022-04-01
卷期号:17 (4): 233-244
被引量:2
标识
DOI:10.2217/rme-2021-0084
摘要
The diagnosis and management of CNS injuries comprises a large portion of psychiatric practice. Many clinical and preclinical studies have demonstrated the benefit of treating CNS injuries using various regenerative techniques and materials such as stem cells, biomaterials and genetic modification. Therefore it is the goal of this review article to briefly summarize the pathogenesis of CNS injuries, including traumatic brain injuries, spinal cord injuries and cerebrovascular accidents. Next, we discuss the role of natural recovery and regeneration of the CNS, explore the relevance in clinical practice and discuss emerging and cutting-edge treatments and current barriers in the field of regenerative medicine.When a person gets a cut on their skin, the human body can usually repair this injury on its own, allowing this tissue to return to normal function. In some cases, when the central nervous system (CNS) is damaged, the human body’s regenerative capabilities are not sufficient to repair it. There are numerous treatments being explored in the field of regenerative medicine that have the potential to assist the human body in repairing the CNS after significant injury and to improve functionality. This paper explores how pharmacological and stem cell treatments, genetic modifications and implantable biomaterials can help repair damage to the CNS by replacing lost tissue and creating an environment that enhances healing.
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