Synthesis of Quinoline N‐Oxides by Cobalt‐Catalyzed Annulation of Arylnitrones and Alkynes

Abstract A new and straightforward protocol for the synthesis of quinoline N ‐oxides from the annulation of arylnitrones and alkynes is described. For the first time, a [4+2] cyclization of nitrone and alkynes has been achieved by cobalt catalysis via a nitrone‐assisted dual C–H cleavage under relatively mild conditions. magnified image