Prediction of Lymph Node Metastasis in Non–Small Cell Lung Carcinoma Using Primary Tumor Somatic Mutation Data

ML models leveraging primary tumor SNP data can enhance LNM prediction in NSCLC, outperforming traditional diagnostic methods. These findings underscore the potential of integrating genomics and ML to develop noninvasive biomarkers, enabling precise risk stratification and personalized treatment strategies in oncology.