1,3,5‐Triformylphloroglucinol Derived β‐Ketoenamine‐Linked Functional Covalent Organic Frameworks with Enhanced Crystallinity and Stability–Recent Advances

Crystallinity, stability, and complexity are significant factors to consider in the design and development of covalent organic frameworks (COFs). Among various building blocks used, 1,3,5-triformylphloroglucinol (Tp) is notable for enhancing both crystallinity and structural stability in COFs. Tp facilitates the formation of β-ketoenamine-linked COFs through keto-enol tautomerism when reacted with aromatic amines. This review article examines the stability, crystallinity, and flexibility of synthetic methodologies involving Tp-based COFs, while highlighting their recent applications. We emphasize the critical roles of non-covalent interactions and keto-enol tautomerism in achieving high levels of crystallinity and stability. Additionally, the diverse and straightforward synthesis methods available for Tp-based COFs contribute to the prevalence of 1,3,5-triformylphloroglucinol in COF development. We conclude by addressing the challenges and future prospects in this area, underscoring the significant potential of Tp-based COFs for environmental and energy-related applications due to their exceptional structural tunability and functionality.