二氢叶酸还原酶
喹唑啉
胸苷酸合酶
化学
酶
生物化学
细胞生长
金黄色葡萄球菌
嘌呤代谢
生物合成
反叶绿体
立体化学
抗代谢物
癌症
生物
细菌
毒性
氟尿嘧啶
遗传学
有机化学
作者
Zihao Zhu,C. F. Chen,Jie Zhang,Fangfang Lai,Feng Jing,Guangxu Wu,Jie Xia,Wenxuan Zhang,Zunsheng Han,Chi Zhang,Qingyun Yang,Yuchen Wang,Bo Liu,Tianlei Li,Song Wu
标识
DOI：10.1021/acs.jmedchem.3c00891
摘要
showed a strong efficacy in a murine model of breast cancer, which was better than the effects of taxol. The findings showcased in this study highlight the promising capabilities of novel DHFR inhibitors in addressing bacterial infections as well as breast cancer.
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(2025-6-4)
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